Sodium Methoxide → HCID 66995618, compound

HRID 1675620Notes

Reaction equation

HRID 1675620 reaction equation
[CH3:1][O-:2].[Na+].F[C:5]1[CH:10]=[CH:9][C:8]([C:11]([F:14])([F:13])[F:12])=[CH:7][C:6]=1[O:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>CO>[CH2:16]([O:15][C:6]1[CH:7]=[C:8]([C:11]([F:14])([F:13])[F:12])[CH:9]=[CH:10][C:5]=1[O:2][CH3:1])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 66995933HCID 66995933, compound

Product 1

HCID 66995618HCID 66995618, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A solution of sodium methoxide in methanol (25% wt, 20 ml) and the product from step (i) (1.20 g) was heated at 100° C. for 3 h. The mixture was quenched with water (100 ml) and the solid was filtered and dried, yield 1.28 g.

Workup

  1. customThe mixture was quenched with water (100 ml)
  2. filtrationthe solid was filtered
  3. customdried

Sources & evidence

ORD record
ord-9dbbf070b55749658024bb3faf09859e
Source dataset
uspto-grants-2011_08
Patent number
US08003703B2

Reaction notes

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