Sodium Carbonate → Diisobutylphosphinic acid

HRID 1675640Notes

Reaction equation

HRID 1675640 reaction equation
C([O-])([O-])=O.[Na+].[Na+].[CH2:7]([PH:11](=[O:13])[OH:12])[CH:8]([CH3:10])[CH3:9]>>[CH2:7]([P:11]([CH2:7][CH:8]([CH3:10])[CH3:9])(=[O:12])[OH:13])[CH:8]([CH3:10])[CH3:9]

Participants

3

Reactant 2

HCID 10340Sodium CarbonateHCID 178454910HCID 178454910, compound

Product 1

HCID 10233207Diisobutylphosphinic acid

Procedure

The concentration of acid was determined by 31P NMR. 10% Na2CO3 solution was prepared in an amount sufficient to neutralize monoisobutylphosphinic acid. The oily fraction in the wash tank was washed with Na2CO3 solution in several portions each time separating the bottom aqueous layer from the wash tank. When removal of sodium monoisobutylphosphinate was completed, as monitored by 13P NMR, the additional water wash was performed on the remaining diisobutylphosphinic acid. The remaining water and toluene were removed under vacuum.

Workup

  1. customwas prepared in an amount sufficient
  2. washThe oily fraction in the wash tank was washed with Na2CO3 solution in several portions each time
  3. customseparating the bottom aqueous layer from the wash tank
  4. customWhen removal of sodium monoisobutylphosphinate
  5. washthe additional water wash
  6. customThe remaining water and toluene were removed under vacuum

Sources & evidence

ORD record
ord-d9ff383e7eb642159b65ef46d57240b4
Source dataset
uspto-grants-2011_08
Patent number
US08003722B2

Reaction notes

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