HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide dimethyl acetal → N'-(4-BroMo-2-cyanophenyl)-N,N-diMethylforMiMidaMide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Reactant | 2-Amino-5-bromobenzonitrile | HCID 429740 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | N'-(4-BroMo-2-cyanophenyl)-N,N-diMethylforMiMidaMide | HCID 57857968 | 85.3% |
Reaction Steps
59 g (300 mmol) of 2-cyano-4-bromoaniline are suspended in 35 ml of dimethylformamide dimethyl acetal (780 mmol) and heated under reflux for 1.5 h. The resulting mixture is cooled and then 300 ml of hexane are added. The resulting solid is filtered off and washed with hexane. 64.5 g (85%) of the desired product are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08003787B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-792904f5843f4ab5a7bd557ffcb17e67 |
| Source note | uspto-grants-2011_08 |