HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Amino-4-fluoro-2-methylphenol → HCID 57857954, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Amino-4-fluoro-2-methylphenol | HCID 10154098 | — |
| Reactant | N'-(4-BroMo-2-cyanophenyl)-N,N-diMethylforMiMidaMide | HCID 57857968 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 57857954 | HCID 57857954 | 58% |
Reaction Steps
5.0 g (19.9 mmol) of N′-(4-bromo-2-cyanophenyl)-N,N-dimethylformamidine and 3.09 g (21.9 mmol) of 5-amino-4-fluoro-2-methylphenol are suspended in 25 ml of acetic acid and heated under reflux for 1 h. The solid obtained after cooling is filtered off and washed with hexane. 4.02 g (58%) of the desired product are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08003787B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-a23c675dd7f34bf1b9dc05b061e236d9 |
| Source note | uspto-grants-2011_08 |