HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-5,6-di(nitrooxy)hexanoic acid → (3R,3aR,6R,6aR)-6-hydroxyhexahydrofuro[3,2-b]furan-3-yl 3-(2,3-bis(nitrooxy)propoxy)propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-5,6-di(nitrooxy)hexanoic acid | HCID 29923588 | — |
| Reactant | 3-(2,3-Bis(nitrooxy)propoxy)propanoic acid | HCID 86645940 | — |
| Product | (3R,3aR,6R,6aR)-6-hydroxyhexahydrofuro[3,2-b]furan-3-yl 3-(2,3-bis(nitrooxy)propoxy)propanoate | HCID 59509508 | — |
Reaction Steps
The title compound was prepared by following the procedure for the synthesis of EXAMPLE 4, except that in Step F the reagent (S)-5,6-di(nitrooxy)hexanoic acid was replaced by 3-(2,3-bis(nitrooxy)propoxy)propanoic acid obtained as described in Oscar Pamies and Jan-E. Backvall, J. Org. Chem. 2002, 67, 1261-1265) and EXAMPLE 10.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08003811B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-5bef3531bb1c4ab89b7e45a51ccf0d12 |
| Source note | uspto-grants-2011_08 |