HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-{5-[(4-aminobenzoyl)amino]-1H-benzimidazol-1-yl}-3-phenylpropanoate → 3-{5-[(4-Aminobenzoyl)amino]-1H-benzimidazol-1-yl}-3-phenylpropanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-{5-[(4-aminobenzoyl)amino]-1H-benzimidazol-1-yl}-3-phenylpropanoate | HCID 58653682 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 3-{5-[(4-Aminobenzoyl)amino]-1H-benzimidazol-1-yl}-3-phenylpropanoic acid | HCID 58653677 | — |
Reaction Steps
A solution of ethyl 3-{5-[(4-aminobenzoyl)amino]-1H-benzimidazol-1-yl}-3-phenylpropanoate (50 mg, 117 μmol) was dissolved in hydrochloric acid (25 mL of a 5N solution), and stirred at room temperature for 110 hours. The solution was evaporated in vacuo to afford the title compound, [LCMS (Method A, Mobile Phase II) RT=3.27 min, MH+ 401].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08003806B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-a08cba4d61294ea5af4cb21716476dd1 |
| Source note | uspto-grants-2011_08 |