Acetonitrile → HCID 11711059, compound

Participants

Reaction Steps

A solution of ethyl 3-{5-[(anilinocarbonyl)amino]-1H-benzimidazol-1-yl}-3-phenylpropanoate (491 mg, 1.14 mmol) in a mixture of hydrochloric acid (40 mL of a 5N solution) and acetonitrile (20 mL) was stirred at room temperature for 24 hours. Additional aliquotes of hydrochloric acid (20 mL of a 5N solution) and acetonitrile (10 mL) were then added, and stirring was continued for a further 72 hours. The solution was then evaporated in vacuo to afford the title compound, [LCMS (Method A, Mobile Phase I) RT=4.11 min, MH+ 401].

Provenance & Evidence