2,6-Dimethoxybenzoic Acid → HCID 11503209, compound

HRID 1676056Notes

Reaction equation

HRID 1676056 reaction equation
[NH2:1][C:2]1[CH:23]=[CH:22][C:5]2[N:6]([CH:9]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH2:10][C:11]([O:13]CC)=[O:12])[CH:7]=[N:8][C:4]=2[CH:3]=1.[CH3:24][O:25][C:26]1[CH:34]=[CH:33][CH:32]=[C:31]([O:35][CH3:36])[C:27]=1[C:28]([OH:30])=O>>[CH3:36][O:35][C:31]1[CH:32]=[CH:33][CH:34]=[C:26]([O:25][CH3:24])[C:27]=1[C:28]([NH:1][C:2]1[CH:23]=[CH:22][C:5]2[N:6]([CH:9]([C:16]3[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=3)[CH2:10][C:11]([OH:13])=[O:12])[CH:7]=[N:8][C:4]=2[CH:3]=1)=[O:30]

Participants

3

Reactant 2

HCID 151092,6-Dimethoxybenzoic AcidHCID 67351926ethyl 3-(5-amino-1H-benzimidazol-1-yl)-3-phenylpropanoate

Product 1

HCID 11503209HCID 11503209, compound

Procedure

Using the procedure of Preparation 21, the title compound (31 mg) was prepared from ethyl 3-(5-amino-1H-benzimidazol-1-yl)-3-phenylpropanoate and 2,6-dimethoxybenzoic acid. [LCMS (Method C, Mobile Phase I) RT=2.25 min, MH+ 446].

Workup

  1. customthe procedure of Preparation 21

Sources & evidence

ORD record
ord-6a1ae7cdb8cf4508b6fb65f0ed96ea47
Source dataset
uspto-grants-2011_08
Patent number
US08003806B2

Reaction notes

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