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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1676088Generated: November 2, 2026

HCID 58653671, compound → 3-(5-Amino-1H-benzimidazol-1-yl)-3-(1,1'-biphenyl)-4-ylpropanoic acid

https://huagongshe.com/reaction/1676088

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 58653671HCID 58653671—
SolventHydrochloric AcidHCID 313—
Product3-(5-Amino-1H-benzimidazol-1-yl)-3-(1,1'-biphenyl)-4-ylpropanoic acidHCID 58653701—

Reaction Steps

A solution of methyl 3-(5-amino-1H-benzimidazol-1-yl)-3-(1,1′-biphenyl)-4-ylpropanoate (10 mg, 27 μmol) in hydrochloric acid (10 mL of a 5N solution) was stirred at room temperature for 48 hours. The solution was then evaporated in vacuo to afford the title compound, [LCMS (Method A, Mobile Phase I) RT=4.11 min, MH+ 358].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08003806B2
Source datasetuspto-grants-2011_08
ORD IDord-6031a80ceb8e4fc4b5b85bef5e1acb38
Source noteuspto-grants-2011_08