Methyl 4-hydroxy-2-methoxybenzoate → 4-(2-Tert-butoxycarbonylethyl)-2-methoxybenzoic acid

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The title compound is prepared in analogy to 4-(2-tert-butoxycarbonyl-ethyl)-3,5-dimethyl-benzoic acid starting from 4-hydroxy-2-methoxy-benzoic acid methyl ester; LC-MS: tR=0.94 min, [M+1]+=281.23; 1H NMR (CDCl3): δ 1.34 (s, 9 H), 2.40-2.47 (m, 2 H), 2.76-2.85 (m, 2 H), 3.83 (s, 3 H), 7.21-7.28 (dd, J=7.6, 3.2 Hz, 1 H), 7.41-7.49 (m, 2 H).

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