HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 4-(1-(4-(methylsulfonyl)phenyl)-2-oxo-1,2-dihydropyridin-4-yloxy)piperidine-1-carboxylate → 4-(Piperidin-4-yloxy)pyridin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 4-(1-(4-(methylsulfonyl)phenyl)-2-oxo-1,2-dihydropyridin-4-yloxy)piperidine-1-carboxylate | HCID 25204174 | — |
| Reactant | Tert-butyl 4-(2-oxo-1,2-dihydropyridin-4-yloxy)piperidine-1-carboxylate | HCID 67366878 | — |
| Product | 4-(Piperidin-4-yloxy)pyridin-2(1H)-one | HCID 67366159 | — |
Reaction Steps
4-(Piperidin-4-yloxy)pyridin-2(1H)-one was prepared according to procedures described in Example 106 Step A substituting tert-butyl 4-(2-oxo-1,2-dihydropyridin-4-yloxy)piperidine-1-carboxylate for tert-butyl 4-(1-(4-(methylsulfonyl)phenyl)-2-oxo-1,2-dihydropyridin-4-yloxy)piperidine-1-carboxylate. MS (EST) 195 (M+H),
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08003796B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-a85d88cc70e84d26bb96ac00c2b2f5f5 |
| Source note | uspto-grants-2011_08 |