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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 167645Generated: October 30, 2026

Dimethylformamide → (1SR,3RS,4SR)-3-{[(5-chloro-thiophene-2-carbonyl)-amino]-methyl}-4-hydroxy-cyclopentanecarboxylic acid methyl ester

https://huagongshe.com/reaction/167645

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantEthyl AcetateHCID 8857—
ReactantDiisopropylethylamineHCID 81531—
Reactant5-Chloro-2-thiophenecarboxylic acidHCID 95048—
ReactantMethyl 3-(aminomethyl)-4-hydroxycyclopentane-1-carboxylateHCID 68685423—
Product(1SR,3RS,4SR)-3-{[(5-chloro-thiophene-2-carbonyl)-amino]-methyl}-4-hydroxy-cyclopentanecarboxylic acid methyl esterHCID 68687973—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-f1111afecde349bf9d28ba442ad17698
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)