Formaldehyde → HCID 86637497, compound

Participants

Reaction Steps

To the mixture of 8.8 g (0.74 mole) benzotriazole and 10 g (0.74 mole) of phenylpropylamine in 200 mL of dichloromethane was added dropwise 6.0 mL (0.74 mole) of 37% aqueous formaldehyde. The reaction mixture was stirred at room temperature overnight. The solution was dried over calcium chloride, filtered and concentrated under pressure. Hexane was added under ice-cooled bath and the resulting solid was collected by filtration and washed with hexane dried to give 21.0 g of benzotriazol-1-ylmethyl-(3-phenyl-propyl)-amine as an oil.

Provenance & Evidence