HCID 58566937, compound → HCID 16770078, compound

Participants

Reaction Steps

4-(2-benzyloxy-acetylamino)-benzoic acid methyl ester 12 (10 grams, 33.44 mmol) is dissolved in methanol (100 mL) in a pressure vessel. Pd/C (10%, 3 grams) is added, and the mixture is stirred under an atmosphere of hydrogen (4 Kg) for 5 hours. The catalyst is removed by filtration and the methanol distilled off. The crude 13 can be purified in a suitable solvent.

Provenance & Evidence