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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1676921Generated: October 28, 2026

Piretanide → HCID 11648571, compound

https://huagongshe.com/reaction/1676921

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiretanideHCID 4849—
ReactantSodium IodideHCID 5238—
ReactantTriethylamineHCID 8471—
ReactantChloro-N,N-diethylacetamideHCID 16844—
SolventDimethylformamideHCID 6228—
ProductHCID 11648571HCID 11648571—

Reaction Steps

In a similar manner to Example 6, piretanide can be reacted with 2-chloro-N,N-diethylacetamide, triethylamine and sodium iodide in dimethylformamide (DMF) to yield N,N-diethylaminocarbonylmethyl 3-aminosulfonyl-4-phenoxy-5-(1-pyrrolidinyl)benzoate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008283B2
Source datasetuspto-grants-2011_08
ORD IDord-95fbf7d965b04569ba2f3d4a4d7f2217
Source noteuspto-grants-2011_08