Piretanide → HCID 11533588, compound

HRID 1676924Notes

Reaction equation

HRID 1676924 reaction equation
[CH:1]1[CH:2]=[CH:3][C:4]([O:7][C:8]2[C:9]([N:21]3[CH2:25][CH2:24][CH2:23][CH2:22]3)=[CH:10][C:11]([C:18]([OH:20])=[O:19])=[CH:12][C:13]=2[S:14]([NH2:17])(=[O:16])=[O:15])=[CH:5][CH:6]=1.[OH-].[CH2:27]([N+:34]([CH3:37])([CH3:36])[CH3:35])[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1>>[NH2:17][S:14]([C:13]1[CH:12]=[C:11]([CH:10]=[C:9]([N:21]2[CH2:25][CH2:24][CH2:23][CH2:22]2)[C:8]=1[O:7][C:4]1[CH:5]=[CH:6][CH:1]=[CH:2][CH:3]=1)[C:18]([O-:20])=[O:19])(=[O:16])=[O:15].[CH2:27]([N+:34]([CH3:37])([CH3:36])[CH3:35])[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1

Participants

3

Reactant 2

HCID 4849PiretanideHCID 66854Benzyltrimethylammonium hydroxide

Product 1

HCID 11533588HCID 11533588, compound

Procedure

In a similar manner to Example 9, piretanide can be reacted with benzyltrimethylammonium hydroxide to yield benzyltrimethylammonium 3-aminosulfonyl-4-phenoxy-5-(1-pyrrolidinyl)benzoate.

Sources & evidence

ORD record
ord-46f5438e57ee47e2afb9ac5cc00c77f9
Source dataset
uspto-grants-2011_08
Patent number
US08008283B2

Reaction notes

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