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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1676927Generated: October 31, 2026

Piretanide → HCID 11719866, compound

https://huagongshe.com/reaction/1676927

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiretanideHCID 4849—
ReactantSodium IodideHCID 5238—
ReactantTriethylamineHCID 8471—
ReactantChloromethyl pivalateHCID 87885—
SolventDimethylformamideHCID 6228—
ProductHCID 11719866HCID 11719866—

Reaction Steps

In a similar manner to Example 12, piretanide can be reacted with chloromethyl pivalate, triethylamine and sodium iodide in DMF to yield_t-butylcarbonyloxymethyl 3-aminosulfonyl-4-phenoxy-5-(1-pyrrolidinyl)benzoate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008283B2
Source datasetuspto-grants-2011_08
ORD IDord-69fefc3cd72f448aaedc1ccbe36d7931
Source noteuspto-grants-2011_08