HuagongsheHuagongshe Chemistry Print Report · For research reference only
Furosemide → Cyanomethyl 5-aminosulfonyl-4-chloro-2-[(2-furanylmethyl)amino]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Furosemide | HCID 3440 | — |
| Reactant | Chloroacetonitrile | HCID 7856 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Cyanomethyl 5-aminosulfonyl-4-chloro-2-[(2-furanylmethyl)amino]benzoate | HCID 11682180 | — |
Reaction Steps
In a similar manner to Example 2, furosemide can be reacted with chloroacetonitrile in DMF to yield cyanomethyl 5-aminosulfonyl-4-chloro-2-[(2-furanylmethyl)amino]-benzoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08008283B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-470e984fcb0749cda017bbec87502a67 |
| Source note | uspto-grants-2011_08 |