HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → Methyl 4-{[4-(methanesulfonyl)benzene-1-sulfonyl]amino}benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Methyl 4-aminobenzoate | HCID 12082 | — |
| Reactant | 4-Methanesulfonylbenzene-1-sulfonyl chloride | HCID 2735182 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | Methyl 4-{[4-(methanesulfonyl)benzene-1-sulfonyl]amino}benzoate | HCID 46534828 | — |
Reaction Steps
For example, 4-amino-benzoic acid methyl ester, is treated with a sulfonyl halide, in this case 4-methanesulfonyl benzenesulfonyl chloride, in a suitable solvent, such as a 1:1 mixture of dichloromethane and pyridine at ambient temperature for 2-24 hours to yield 4-(4-methanesulfonyl-benzenesulfonylamino)-benzoic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08008296B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-5933964f745b49c495e2a62a795e8308 |
| Source note | uspto-grants-2011_08 |