Butylamine → HCID 15951002, compound

HRID 1676946Notes

Reaction equation

HRID 1676946 reaction equation
F[C:2]1[CH:7]=[CH:6][C:5]([C:8]([N:10]2[CH2:14][CH2:13][CH2:12][C@H:11]2[CH2:15][N:16]2[CH2:20][CH2:19][CH2:18][CH2:17]2)=[O:9])=[CH:4][CH:3]=1.[CH2:21]([NH2:25])[CH2:22][CH2:23][CH3:24]>>[CH2:21]([NH:25][C:2]1[CH:7]=[CH:6][C:5]([C:8]([N:10]2[CH2:14][CH2:13][CH2:12][C@H:11]2[CH2:15][N:16]2[CH2:20][CH2:19][CH2:18][CH2:17]2)=[O:9])=[CH:4][CH:3]=1)[CH2:22][CH2:23][CH3:24]

Participants

3

Reactant 2

HCID 8007ButylamineHCID 11965126(4-fluorophenyl)-[(2S)-2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]methanone

Product 1

HCID 15951002HCID 15951002, compound

Procedure

(4-Butylamino-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone is prepared from (4-Fluoro-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone and n-butylamine in a manner substantially similar to Procedure A. MS (APCI+) 330 (MA-H)+.

Sources & evidence

ORD record
ord-5b06d693b4e84d3680117f0c16b8c842
Source dataset
uspto-grants-2011_08
Patent number
US08008296B2

Reaction notes

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