(S)-(+)-1-(2-Pyrrolidinylmethyl)pyrrolidine → [4-(3-Methanesulfonyl-pyrrolidine-1-sulfonyl)-phenyl]-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone

Participants

Reaction Steps

The title compound is prepared from 4-(3-methanesulfonyl-pyrrolidine-1-sulfonyl)-benzoic acid (230 mg, 0.69 mmol) and (S)(+)-1-(2-pyrrolidinylmethyl)pyrrolidine (CAS 51207-66-0)(88 mg, 0.57 mmol) in a manner substantially similar to Procedure G to provide 133 mg (50%) of the title compound. MS (ES+) 470.2 (M+H)+.

Provenance & Evidence