Potassium Carbonate → HCID 67179275, compound

Participants

Reaction Steps

A mixture of 3-iodopyridine (823 mg, 4.01 mmol), methyl-4-mercaptobenzoate (500 mg, 2.97 mmol), potassium carbonate (677 mg, 4.90 mmol), and copper dust (4 mg, 0.653 mmol) in dimethylformamide (10 mL) are heated to reflux temperature for 18 h. The heat is removed and the reaction is filtered through Celite® with dichloromethane. The filtrate is concentrated in vacuo and the residue is recrystallized from ether and hexane to obtain 689 mg (99%) of the title compound. MS (ES+) m/e 232.0 (M+1)+.

Provenance & Evidence