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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1676986Generated: October 30, 2026

Mafenide Hydrochloride → HCID 58659649, compound

https://huagongshe.com/reaction/1676986

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMafenide HydrochlorideHCID 67313—
ReactantMethylamine hydrochlorideHCID 6364545—
Reactantethyl 5-chloro-3-(chlorosulfonyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylateHCID 22401482—
Reactantethyl 3-(chlorosulfonyl)-5-bromo-1-(phenylsulfonyl)-1H-indole-2-carboxylateHCID 86592455—
ProductHCID 58659649HCID 58659649—

Reaction Steps

Following the procedures described in Steps D and E of Example 1, replacing in Step D ethyl 5-chloro-3-(chlorosulfonyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylate with ethyl 5-bromo-3-(chlorosulfonyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylate, and methylamine hydrochloride with 4-(aminomethyl)benzene-sulfonamide hydrochloride, the title compound was obtained. HRMS (ES) exact mass calculated for C16H16BrN4O5S2 (M+H+): 486.9740. Found 486.9749.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008295B2
Source datasetuspto-grants-2011_08
ORD IDord-2b22f406a48b4dcbb243e5d6af76c4af
Source noteuspto-grants-2011_08