HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → HCID 67371800, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 67372260 | HCID 67372260 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 67371800 | HCID 67371800 | — |
Reaction Steps
The material from Example 96, Step C was combined with acetyl chloride (1.1 equivalents) and triethylamine (3 equivalents) in dichloromethane and stirred for for two hours at room temperature. The reaction was diluted with EtOAc, washed with sat NaHCO3 and brine, dried over Na2SO4 and concentrated in vacuo to obtain the titled compound. ESI+ MS: 678 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08008295B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-0b9b56abcc3348b2a231084dbcd88e09 |
| Source note | uspto-grants-2011_08 |