HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Tetrahydro-2H-pyran-2-ylmethyl)amine → HCID 10476984, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Tetrahydro-2H-pyran-2-ylmethyl)amine | HCID 97924 | — |
| Reactant | Methylamine hydrochloride | HCID 6364545 | — |
| Reactant | ethyl 5-chloro-3-(chlorosulfonyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylate | HCID 22401482 | — |
| Reactant | ethyl 3-(chlorosulfonyl)-5-bromo-1-(phenylsulfonyl)-1H-indole-2-carboxylate | HCID 86592455 | — |
| Product | HCID 10476984 | HCID 10476984 | — |
Reaction Steps
Following the procedures described in Steps D and E of Example 1, replacing in Step D ethyl 5-chloro-3-(chlorosulfonyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylate with ethyl 5-bromo-3-(chlorosulfonyl)-1-(phenylsulfonyl)-1H-indole-2-carboxylate, and methylamine hydrochloride with (±)-1-tetrahydro-2H-pyran-2-ylmethanamine, the title compound was obtained. Proton NMR for the product was consistent with the titled compound. ESI+ MS: 415.93 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08008295B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-0671afa463734c78afe8ca9bc6ee42b2 |
| Source note | uspto-grants-2011_08 |