HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Methoxyethyl)piperazine → N-[2-(4-Chloro-phenyl)-ethyl]-6-[4-(2-methoxy-ethyl)-piperazin-1-yl]-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Methoxyethyl)piperazine | HCID 2734638 | — |
| Reactant | 6-chloro-N-[2-(4-chlorophenyl)ethyl]pyridine-3-carboxamide | HCID 8088154 | — |
| Product | N-[2-(4-Chloro-phenyl)-ethyl]-6-[4-(2-methoxy-ethyl)-piperazin-1-yl]-nicotinamide | HCID 57571677 | — |
Reaction Steps
In analogy to example 21.b 6-chloro-N-[2-(4-chloro-phenyl)-ethyl]-nicotinamide was reacted with 1-(2-methoxyethyl)piperazine. Light yellow solid. MS (ISP): 403.3 ([M+H]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08008305B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-8331a09a44c44df1b02c8cf3cac83950 |
| Source note | uspto-grants-2011_08 |