3-Fluorobenzoic Acid → HCID 57571683, compound
Reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][CH:10]=1)[C:5]([OH:7])=O.[Cl:11][C:12]1[CH:13]=[C:14]([CH2:19][CH2:20][NH2:21])[CH:15]=[CH:16][C:17]=1[Cl:18]>>[Cl:11][C:12]1[CH:13]=[C:14]([CH2:19][CH2:20][NH:21][C:5](=[O:7])[C:4]2[CH:8]=[CH:9][CH:10]=[C:2]([F:1])[CH:3]=2)[CH:15]=[CH:16][C:17]=1[Cl:18]Participants
3
Procedure
N-[2-(3,4-Dichloro-phenyl)-ethyl]-3-fluoro-benzamide was prepared in analogy to Example 40 from 3-fluoro-benzoic acid and 2-(3,4-dichloro-phenyl)-ethylamine: yellow solid,
Sources & evidence
- ORD record
- ord-f977f067ee0f462fac0bebb9578e0a44
- Source dataset
- uspto-grants-2011_08
- Patent number
- US08008305B2
Reaction notes
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