3-Phenylpropylamine → 6-Phenylamino-N-(3-phenyl-propyl)-nicotinamide

HRID 1677115Notes

Reaction equation

HRID 1677115 reaction equation
[C:1]1([NH:7][C:8]2[CH:16]=[CH:15][C:11]([C:12]([OH:14])=O)=[CH:10][N:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:17]1([CH2:23][CH2:24][CH2:25][NH2:26])[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[C:1]1([NH:7][C:8]2[CH:16]=[CH:15][C:11]([C:12]([NH:26][CH2:25][CH2:24][CH2:23][C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[O:14])=[CH:10][N:9]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 162593-PhenylpropylamineHCID 27718126-(Phenylamino)nicotinic acid

Product 1

HCID 575716976-Phenylamino-N-(3-phenyl-propyl)-nicotinamide

Procedure

The title compound was prepared in analogy to example 1, but starting from 6-phenylamino-nicotinic acid and using 3-phenyl-propylamine in the third step.

Sources & evidence

ORD record
ord-76f0e28073b947e093fd66b395b94b32
Source dataset
uspto-grants-2011_08
Patent number
US08008305B2

Reaction notes

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