2-(2-Fluorophenyl)ethylamine → HCID 57571687, compound

HRID 1677119Notes

Reaction equation

HRID 1677119 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH2:9][NH2:10].[CH3:11][C:12]1[N:16]([CH2:17][C:18]2[CH:26]=[CH:25][C:21]([C:22](O)=[O:23])=[CH:20][CH:19]=2)[C:15]2[CH:27]=[CH:28][CH:29]=[CH:30][C:14]=2[N:13]=1>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:8][CH2:9][NH:10][C:22](=[O:23])[C:21]1[CH:20]=[CH:19][C:18]([CH2:17][N:16]2[C:15]3[CH:27]=[CH:28][CH:29]=[CH:30][C:14]=3[N:13]=[C:12]2[CH3:11])=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 6433572-(2-Fluorophenyl)ethylamineHCID 6498814HCID 6498814, compound

Product 1

HCID 57571687HCID 57571687, compound

Procedure

The title compound was prepared in analogy to example 1c, but using 2-(2-fluoro-phenyl)-ethylamine and 4-(2-methyl-benzoimidazol-1-ylmethyl)-benzoic acid as coupling components. MS (ISP): 388.2 ((M+H)+.).

Sources & evidence

ORD record
ord-99a0af22a5f240dc84e9c70e3c4ddca3
Source dataset
uspto-grants-2011_08
Patent number
US08008305B2

Reaction notes

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