3-Pyridinylboronic acid → HCID 67372243, compound

HRID 1677160Notes

Reaction equation

HRID 1677160 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3](B(O)O)[CH:2]=1.Br[C:11]1[CH:16]=[CH:15][C:14]([C:17]([N:19]2[CH2:23][CH2:22][CH2:21][C@H:20]2[CH2:24][N:25]2[CH2:29][CH2:28][CH2:27][CH2:26]2)=[O:18])=[C:13]([F:30])[CH:12]=1>>[F:30][C:13]1[C:12]([C:4]2[CH:5]=[CH:6][N:1]=[CH:2][CH:3]=2)=[CH:11][CH:16]=[CH:15][C:14]=1[C:17]([N:19]1[CH2:23][CH2:22][CH2:21][C@H:20]1[CH2:24][N:25]1[CH2:29][CH2:28][CH2:27][CH2:26]1)=[O:18]

Participants

3

Reactant 2

HCID 27343783-Pyridinylboronic acidHCID 11965125(4-Bromo-2-fluoro-phenyl)-((S)-2-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone

Product 1

HCID 67372243HCID 67372243, compound

Procedure

The title compound is prepared in a manner substantially analogous to Procedure FF starting from 3-pyridine boronic acid and (4-bromo-2-fluoro-phenyl)-(2-(S)-pyrrolidin-1-ylmethyl-pyrrolidin-1-yl)-methanone. MS (ES+) 354.2

Sources & evidence

ORD record
ord-0de46709ecd44b94a1f12d366da202a1
Source dataset
uspto-grants-2011_08
Patent number
US08008301B2

Reaction notes

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