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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1677198Generated: November 2, 2026

4-Bromophenyl cyclopropyl ketone → HCID 57980118, compound

https://huagongshe.com/reaction/1677198

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromophenyl cyclopropyl ketoneHCID 81394—
Reactant4-Carboxy-3-fluorophenylboronic acidHCID 2763201—
Reactant(R)-2-methyl-1-((S)-pyrrolidin-2-ylmethyl)pyrrolidineHCID 46911921—
ProductHCID 57980118HCID 57980118—

Reaction Steps

The title compound is prepared in a manner substantially analogous to Procedures QQ and B′ starting from commercially available (4-Bromo-phenyl)-cyclopropyl-methanone and (4-carboxy-3-fluorophenyl)boronic acid (CAS#120153-08-4), then 2-(R)-Methyl-1-(2-(S)-pyrrolidinylmethyl)pyrrolidine. MS (M+H) 435.2

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008301B2
Source datasetuspto-grants-2011_08
ORD IDord-591dc8301cbc459aba291ddaa976a13c
Source noteuspto-grants-2011_08