Water → 5-Bromo-3,4-dihydroxybenzaldehyde

Participants

Reaction Steps

To a solution of 3,4-dihydroxy benzaldehyde (115.48 g, 12 mmol) in 500 ml AcOH was added bromine (6.1 ml, 118 mmol) drop-wise in 50 ml AcOH over 10 min. After 4 h the mixture was poured into cold H2O. The precipitate was filtered, washed with cold H2O and dried in vacuum to give 3-bromo-4,5-dihydroxy-benzaldehyde (11.64 g, 48%) as a grey solid.

Provenance & Evidence