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HRID1677500

反应详情

EQUATION

反应方程式

HRID 1677500 的结构方程式

REACTANTS

反应物

2
结构：Cl.OC1CNC1
HCID2759290

3-Hydroxyazetidine hydrochloride

C3H8ClNO

结构：CC(C)(C)C(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3cccc(I)c3)nc12
HCID59540520

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)C(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3cccc(N4CC(O)C4)c3)nc12
HCID59540988

未命名化合物

PROCEDURE

实验过程

1-[2-[3-(3-Hydroxy-azetidin-1-yl)-phenyl]-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-2,2-dimethyl-propan-1-one was prepared starting from 1-[2-(3-iodo-phenyl)-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-2,2-dimethyl-propan-1-one and azetidin-3-ol hydrogen chloride following the same procedure of RO5364753. M+H=481.