Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1677507Generated: November 1, 2026

HCID 67346423, compound → HCID 59540622, compound

https://huagongshe.com/reaction/1677507

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67346423HCID 67346423—
SolventDichloromethane methanolHCID 21226129—
ProductHCID 59540622HCID 5954062283%

Reaction Steps

3-[7-(2,2-Dimethyl-propionyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-N-(2-hydroxy-ethyl)-5-pyrrolidin-1-yl-benzamide was prepared following the same procedure but using 3-[7-(2,2-dimethyl-propionyl)-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-N-(2-hydroxy-ethyl)-5-pyrrolidin-1-yl-benzamide as starting material. The product was obtained in 83% yield after SiO2 chromatography (DCM/MeOH 0-5% MeOH).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008298B2
Source datasetuspto-grants-2011_08
ORD IDord-053c147816f94cbcb26160171165a727
Source noteuspto-grants-2011_08