HCID 59540637, compound → HCID 59540636, compound

HRID 1677538Notes

Reaction equation

HRID 1677538 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:16]2[N:17]=[C:18]3[C:24]([C:25]([C:27]4([CH3:33])[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]4)=[O:26])=[CH:23][NH:22][C:19]3=[N:20][CH:21]=2)[CH:6]=[C:7]([N:9]2[CH2:14][CH2:13][S:12](=O)[CH2:11][CH2:10]2)[CH:8]=1.O=S1(=O)CCN(C2C=C(C3N=C4C(C(C5(C)CCCCC5)=O)=CNC4=NC=3)C=C(OC)C=2)CC1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:16]2[N:17]=[C:18]3[C:24]([C:25]([C:27]4([CH3:33])[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]4)=[O:26])=[CH:23][NH:22][C:19]3=[N:20][CH:21]=2)[CH:6]=[C:7]([N:9]2[CH2:10][CH2:11][S:12][CH2:13][CH2:14]2)[CH:8]=1

Participants

3

Reactant 2

HCID 59540637HCID 59540637, compoundHCID 59540673HCID 59540673, compound

Product 1

HCID 59540636HCID 59540636, compound

Procedure

MP=212-214, (M+H)+=451; {2-[3-Methoxy-5-(1-oxo-1lambda*4*-thiomorpholin-4-yl)-phenyl]-5H-pyrrolo[2,3-b]pyrazin-7-yl}-(1-methyl-cyclohexyl)-methanone. MP=270-271, (M+H)+=467; {2-[3-(1,1-Dioxo-1lambda*6*-thiomorpholin-4-yl)-5-methoxy-phenyl]-5H-pyrrolo[2,3-b]pyrazin-7-yl}-(1-methyl-cyclohexyl)-methanone. MP=245-247, (M+H)+=483.

Sources & evidence

ORD record
ord-091cf8fe709f45a7ab0a1a8f4227485d
Source dataset
uspto-grants-2011_08
Patent number
US08008298B2

Reaction notes

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