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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1677554Generated: November 2, 2026

2-Azabicyclo(2.1.1)hexane hydrochloride → HCID 59540831, compound

https://huagongshe.com/reaction/1677554

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Azabicyclo(2.1.1)hexane hydrochlorideHCID 55219746—
Reactant1-[2-(3-iodo-phenyl)-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-2,2-dimethyl-propan-1-oneHCID 59540520—
ProductHCID 59540831HCID 59540831—

Reaction Steps

1-[2-[3-(2-Azabicyclo[2.1.1]hex-2-yl)-phenyl]-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-2,2-dimethyl-propan-1-one was prepared from 1-[2-(3-Iodo-phenyl)-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-2,2-dimethyl-propan-1-one and 2-azabicyclo[2.1.1]hexane hydrochloride as described above (34%; MS=361 M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008298B2
Source datasetuspto-grants-2011_08
ORD IDord-479b38d23d144b15859bcc579876b801
Source noteuspto-grants-2011_08