1-(2-Fluoro-5-methylphenyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea → HCID 178426033, compound

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Reaction Steps

1-(2-Fluoro-5-methylphenyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-phenyl]urea is coupled, by Suzuki reaction, with 4-bromo-1H-pyrazolo[4,3-c]pyrid-3-ylamine according to a protocol similar to that for the preparation of Example 3. A yellow powder of 1-[4-(3-amino-1H-pyrazolo[3,4-b]pyrid-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea is obtained, the characteristics of which are as follows:

Provenance & Evidence