HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexyl isocyanate → 2-Oxo-5-trifluoromethylbenzothiazole 3-hexylcarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexyl isocyanate | HCID 75659 | — |
| Reactant | 5-(Trifluoromethyl)benzo[d]thiazol-2(3H)-one | HCID 13227340 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 2-Oxo-5-trifluoromethylbenzothiazole 3-hexylcarboxamide | HCID 131729126 | — |
Reaction Steps
300 mg (1.37 mmol) of 5-trifluoromethyl-3H-benzothiazol-2-one were reacted in analogy to Example 1 with 202 mg (1.37 mmol) of 1-isocyanatohexane in dioxane at 80° C. Yield: 125 mg (26%), M+H+: 347.05.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08008331B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-0aed2a16731546eb9b24a18813762f8c |
| Source note | uspto-grants-2011_08 |