4-Iodo-2,6-dimethylbenzonitrile → 2,6-Dimethyl-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-8-yl)benzonitrile

HRID 1677658Notes

Reaction equation

HRID 1677658 reaction equation
[C:1]1(=O)[C:5]2=[CH:6][CH2:7][CH2:8][CH2:9][N:4]2[CH:3]=[N:2]1.I[C:12]1[CH:19]=[C:18]([CH3:20])[C:15]([C:16]#[N:17])=[C:14]([CH3:21])[CH:13]=1>>[CH3:21][C:14]1[CH:13]=[C:12]([CH:6]2[CH2:7][CH2:8][CH2:9][N:4]3[CH:3]=[N:2][CH:1]=[C:5]23)[CH:19]=[C:18]([CH3:20])[C:15]=1[C:16]#[N:17]

Participants

3

Reactant 2

HCID 118320574-Iodo-2,6-dimethylbenzonitrileHCID 690431796,7-dihydro-5H-imidazo[1,5-a]pyridinone

Product 1

HCID 578143872,6-Dimethyl-4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-8-yl)benzonitrile

Procedure

starting from 6,7-dihydro-5H-imidazo[1,5-a]pyridin-one [426219-51-4] and 4-iodo-2,6-dimethylbenzonitrile [160682-00-8]

Sources & evidence

ORD record
ord-e0e646b9f98d48338ee5013461180819
Source dataset
uspto-grants-2011_08
Patent number
US08008334B2

Reaction notes

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