Hydrogen Peroxide → HCID 58138771, compound

Participants

Reaction Steps

To a suspension of 1-(4-fluoro-phenyl)-1H-indazole-4-carboxylic acid 2-chloro-4-cyano-benzylamide in a 1:1 mixture of EtOH—H2O (2.0 mL) was added KOH (0.018 g, 0.32 mmol) and a 30% solution of H2O2 in H2O (0.13 mL, 1.1 mmol). The suspension was sealed and heated briefly to dissolve the mixture. The resultant solution was stirred at room temperature for 16 hours, during which time a solid precipitated. The mixture was diluted with H2O (10 mL) and the solid was collected by filtration and dried to afford the title compound as a white powder.

Provenance & Evidence