Hydrazine → HCID 66886660, compound

Participants

Reaction Steps

To a solution of N-[1-(1-benzyl-5-methyl-1H-benzimidazol-2-yl)-2-methyl-propyl]-N-[3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propyl]-4-methyl-benzamide (0.302 mmol) in ethanol at room temperature, was added hydrazine (0.19 mL, 6 mmol). The reaction was stirred at room temperature for 1 h. The crude product was purified via reverse phase chromatography to give N-(3-amino-propyl)-N-[1-(1-benzyl-5-methyl-1H-benzimidazol-2-yl)-2-methyl-propyl]-4-methyl-benzamide (129 mg).

Provenance & Evidence