Water → HCID 57894427, compound

Participants

Reaction Steps

To a solution of product of step 9 (0.1 mmol) in 2 mL of anhydrous DCM at 0° C., was added DMAP (0.01 mmol), Et3N (0.4 mmol), and p-toluoyl chloride (0.4 mmol). The mixture was stirred at room temperature for 1 h. The solution was poured into water, and extracted with EtOAc (×3). The organic layers were combined, washed with H2O (×3), brine (×3), dried (Na2SO4), filtered, and the filtrate was concentrated. The material was purified by flash chromatography (10% EtOAc:hexane) to yield 50 mg of title compound.

Provenance & Evidence