Water → HCID 11590985, compound

Participants

Reaction Steps

To a solution of product of step 10 (50 mg) in 1 mL of EtOH was added hydrazine (0.1 mL). The mixture was stirred at room temperature for 2 h. The solution was poured into water, and extracted with EtOAc (×3). The organic layers were combined, washed with 10% NaOH aq., H2O (×3), brine (×3), dried (Na2SO4), filtered, and the filtrate was concentrated. The material was purified preparatory HPLC to give N-(3-aminopropyl)-N-[1-(1-benzyl-5-chloro-1H-indol-2-yl)-2-methylpropyl]benzamide.

Provenance & Evidence