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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1677894Generated: October 31, 2026

(R)-2-Tosyloxypropionic acid methyl ester → methyl (2S)-2-{[3'-chloro-5-fluoro-4'-(phenylsulfonyl)biphenyl-2-yl]oxy}propanoate

https://huagongshe.com/reaction/1677894

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-2-Tosyloxypropionic acid methyl esterHCID 12884153—
Reactant3'-Chloro-5-fluoro-4'-(phenylsulfonyl)biphenyl-2-olHCID 67240365—
Productmethyl (2S)-2-{[3'-chloro-5-fluoro-4'-(phenylsulfonyl)biphenyl-2-yl]oxy}propanoateHCID 67239082—

Reaction Steps

The subtitle compound was prepared by the method of example 11 step (vii) using the product of step (iii) and the product of example 11 step (vi).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008350B2
Source datasetuspto-grants-2011_08
ORD IDord-3fc6831d0a05414f8895d8c4232920c9
Source noteuspto-grants-2011_08