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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1677899Generated: October 26, 2026

5-Chloro-2-methoxyphenylboronic acid → 5'-Chloro-3,5-difluoro-2'-methoxybiphenyl-4-yl phenyl sulfone

https://huagongshe.com/reaction/1677899

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chloro-2-methoxyphenylboronic acidHCID 2735751—
Reactant4-Bromo-2,6-difluorophenyl phenyl sulfoneHCID 68436269—
Product5'-Chloro-3,5-difluoro-2'-methoxybiphenyl-4-yl phenyl sulfoneHCID 67240070—

Reaction Steps

The subtitle compound was prepared by the method of example 2 step (ii) using the product of step (i) and 5-chloro-2-methoxybenzene boronic acid which was used directly in step (iv) without further characterisation.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008350B2
Source datasetuspto-grants-2011_08
ORD IDord-ba7523d118174100ba79e14628203b3d
Source noteuspto-grants-2011_08