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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 167798Generated: October 25, 2026

Tetrahydrofuran → 4-fluoro-N-[1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-1-[4-fluoro-3-(trifluoromethyl)phenyl]-2-[4-(hydroxymethyl)phenyl]ethyl]-3-(trifluoromethyl)benzamide

https://huagongshe.com/reaction/167798

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantTriethylboranuideHCID 2723994—
ReactantMethyl 4-[2-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-[[4-fluoro-3-(trifluoromethyl)benzoyl]amino]-2-[4-fluoro-3-(trifluoromethyl)phenyl]ethyl]benzoateHCID 72291259—
Product4-fluoro-N-[1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-1-[4-fluoro-3-(trifluoromethyl)phenyl]-2-[4-(hydroxymethyl)phenyl]ethyl]-3-(trifluoromethyl)benzamideHCID 74065148—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-67951e9c17774724868377ce355df731
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)