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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1678120Generated: November 3, 2026

Azepane → HCID 59754753, compound

https://huagongshe.com/reaction/1678120

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAzepaneHCID 8119—
Reactant2-chloro-1-phenyl-1H-indole-3-carbaldehydeHCID 314793—
ProductHCID 59754753HCID 5975475342%

Reaction Steps

2-Chloro-1-phenyl-1H-indole-3-carboxaldehyde is reacted with azepane as described in Example 2 to give the title compound (42% yield). NMR (CDCl3) 10.25 (1H, s), 8.23 (1H, d), 7.58 (2H, m), 7.51 (1H, m), 7.39 (2H, d), 7.25 (1H, m), 7.15 (1H, t), 6.98 (1H, d), 3.50 (4H, m), 2.55 (4H, m), 2.33 (3H, s), 1.78 (2H, m).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008491B2
Source datasetuspto-grants-2011_08
ORD IDord-9334fb4b7a0e4f71ae32522bf0c1c980
Source noteuspto-grants-2011_08