tert-butyl N-[2-amino-4-[2-(4-fluorophenyl)ethynyl]-5-[(2-methylpropan-2-yl)oxy]phenyl]carbamate → tert-butyl N-[4-[2-(4-fluorophenyl)ethynyl]-5-[(2-methylpropan-2-yl)oxy]-2-[[3-oxo-3-[3-(triazol-1-yl)phenyl]propanoyl]amino]phenyl]carbamate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH2:28])[cH:10][c:11]([C:19]#[C:20][c:21]2[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]2)[c:12]([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[cH:13]1)=[O:29].[CH2:30]([O:32][C:33](=[O:31])[CH2:34][C:35]([c:36]1[cH:37][c:38](-[n:42]2[n:43][n:44][cH:45][cH:46]2)[cH:39][cH:40][cH:41]1)=[O:47])[CH3:48]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][c:8]1[c:9]([NH:28][C:33](=[O:32])[CH2:34][C:35]([c:36]2[cH:37][c:38](-[n:42]3[n:43][n:44][cH:45][cH:46]3)[cH:39][cH:40][cH:41]2)=[O:47])[cH:10][c:11]([C:19]#[C:20][c:21]2[cH:22][cH:23][c:24]([F:27])[cH:25][cH:26]2)[c:12]([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[cH:13]1)=[O:29]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-7d96314a8a7047f5840d815c3a83d40f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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