HCID 59024336, compound → HCID 59023761, compound

Participants

Reaction Steps

Starting with 7-benzo[b]thiophen-2-yl-5-bromo-1-(2-trimethylsilanyl-ethoxymethyl)-1H-indazole (Preparation #23, 0.2 g, 0.435 mmol) and using the procedure for the preparation of (7-benzo[b]thiophen-2-yl-1H-indazol-3-yl)-pyridin-2-yl-methanone (Preparation #52 above) provided (7-benzo[b]thiophen-2-yl-1H-indazol-5-yl)-pyridin-2-yl-methanone (17 mg, 11%); (DMSO-d6, 400 MHz) δ 8.79 (d, 1H), 8.65 (s, 1H), 8.54 (s, 1H), 8.27 (s, 1H), 8.24 (s, 1H), 8.11 (m, 1H), 8.05 (m, 2H), 7.95 (m, 1H), 7.72 (m, 1H), 7.45 (m, 2H); RP-HPLC (Table 1, Method e) Rt 2.28 min; m/z: (M−H)− 354.1.

Provenance & Evidence