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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 167840Generated: October 31, 2026

2-Fluoro-5-(trifluoromethyl)phenyl isocyanate → 1-(4-(2,3-Dioxo-1,2,3,4-tetrahydropyrido[3,2-b]pyrazin-8-yloxy)-2-fluorophenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea

https://huagongshe.com/reaction/167840

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-(trifluoromethyl)phenyl isocyanateHCID 2733380—
Reactant8-(4-Amino-3-fluorophenoxy)pyrido[3,2-b]pyrazine-2,3(1H,4H)-dioneHCID 59588875—
Product1-(4-(2,3-Dioxo-1,2,3,4-tetrahydropyrido[3,2-b]pyrazin-8-yloxy)-2-fluorophenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)ureaHCID 44132849—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-8282f0a4fd374bc38f2545f4f90c7b6e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)